No, but you need a plan, and the plan depends on how low. Medical schools weigh your science GPA heavily, and many quietly screen out applicants whose cumulative or science GPA falls below about 3.0. If you are under that line, the first job is raising it with a post-bacc, which is additional undergraduate science coursework that flows directly into your application GPA.
If your GPA sits in the 3.0 to 3.4 range, a strong post-bacc or a Special Master's Program can prove you handle rigorous work. An SMP builds a separate graduate record and is high risk and high reward: do well and you show schools exactly what they want to see. DO schools are also more forgiving of a low GPA, and some offer grade replacement that softens old failures.
A single rough semester followed by a clear upward trend is a story admissions committees understand and forgive. A low GPA is a detour, not a wall.